Genetic and genomic studies of the parasitic nematode Strongyloides spp. - the human parasite S. stercoralis and the laboratory model species S. papillosus

The parasitic nematode genus Strongyloides contains an important human pathogen and many animal parasitic species, which can serve as models for basic and applied research. Strongyloides spp. undergo a unique and complex life cycle, which includes easily accessible sexual free-living generations in between asexual parasitic generations. In this thesis I present two project, one with a more applied focus on human parasite S. stercoralis, and the other on basic biological questions within the sheep parasite S. papillosus

Writing Features Influencing Non-Native English Speakers’ Publication in International Journals

Given that more and more non-native English speakers have begun to publish in English in recent years, researchers are becoming increasingly interested in revealing writing features that influence the eligibility for international publication. This paper, with systematic review as the major research method, aims to outline factors influencing non-native speaker’s publication in international journals. Based on critical analysis of previous research findings presented in six representative papers, the research draws to the following conclusions: first, even though journal editors prefer correct grammar use, minor grammar errors do not decrease the possibility of publication, because more attention is paid to the worthiness of the content, which may include uniqueness of viewpoint, high research quality, discursive coherence in paper structuring and content organizing, etc. In the second place, avoiding time delay has a significantly positive impact on the likelihood of publication. Thirdly, research that has a clear social background is easier to be accepted by international journals than research without any social background or without explicitly demonstrated social background. Last but not least, compared with those from America, Britain and Western Europe, voices from Asia, Africa and other non-Western countries are particularly welcome. However, since the present research draws heavily on material from the fields of science and engineering, research findings may vary once other fields have been included

Writing Features Influencing Non-Native English Speakers’ Publication in International Journals

Given that more and more non-native English speakers have begun to publish in English in recent years, researchers are becoming increasingly interested in revealing writing features that influence the eligibility for international publication. This paper, with systematic review as the major research method, aims to outline factors influencing non-native speaker’s publication in international journals. Based on critical analysis of previous research findings presented in six representative papers, the research draws to the following conclusions: first, even though journal editors prefer correct grammar use, minor grammar errors do not decrease the possibility of publication, because more attention is paid to the worthiness of the content, which may include uniqueness of viewpoint, high research quality, discursive coherence in paper structuring and content organizing, etc. In the second place, avoiding time delay has a significantly positive impact on the likelihood of publication. Thirdly, research that has a clear social background is easier to be accepted by international journals than research without any social background or without explicitly demonstrated social background. Last but not least, compared with those from America, Britain and Western Europe, voices from Asia, Africa and other non-Western countries are particularly welcome. However, since the present research draws heavily on material from the fields of science and engineering, research findings may vary once other fields have been included

A Brief Talk on Chinglish from the Level of Teaching Methods

China has been promoting English teaching activities since the 1960s with the goal of cultivating a global perspective and proficiency among the younger generation. Despite decades of teaching, issues such as the inconsistent use of British and American pronunciation and the incorrect use of tenses in Chinese English persist and have not seen improvement. This paper delves into a comprehensive study from the perspective of the differences between English teaching in China and foreign countries, specifically exploring the relationship between Chinese English and educational methods while analyzing the underlying logic and differences in Chinese and Western English teaching methods. This paper starts with the scientific laws of language acquisition and aims to provide practical solutions to address Chinese English problems and other language-related issues, and offers valuable insights into the innovation and development of Chinese English teaching in the future

高齢者の健康管理におけるウェアラブルデバイスと中国伝統医学の役割

早大学位記番号:新8258早稲田大

Zero-Shot 3D Drug Design by Sketching and Generating

Drug design is a crucial step in the drug discovery cycle. Recently, various deep learning-based methods design drugs by generating novel molecules from scratch, avoiding traversing large-scale drug libraries. However, they depend on scarce experimental data or time-consuming docking simulation, leading to overfitting issues with limited training data and slow generation speed. In this study, we propose the zero-shot drug design method DESERT (Drug dEsign by SkEtching and geneRaTing). Specifically, DESERT splits the design process into two stages: sketching and generating, and bridges them with the molecular shape. The two-stage fashion enables our method to utilize the large-scale molecular database to reduce the need for experimental data and docking simulation. Experiments show that DESERT achieves a new state-of-the-art at a fast speed.Comment: NeurIPS 2022 camera-read